A beautiful paper from Hasse lab at EMBL Barcelona modelling fibrosis in the lung and heart to study the implications of fibrosis on microvasculature. They used a macro-scale side-by-side channel chip, previously developed in the lab of Roger Kamm. The authors developed this vasculature on a chip to assess...
This recently published paper from Musah lab at Duke university is a beautiful validation of using kidney on a chip to model glomerular filtration. This tissue chip was lined by epithelial and endothelial cells to mimic the blood filtration barrier and selective molecular filtration function of the kidney. Using...
A recently published paper from Hesperos Inc./Hickman lab at University of Central Florida co-culturing human hepatocytes and adipocytes representing white adipose tissue. In this multi-organ on a chip different serum-free media formulations were used to represent different human metabolic states. Results The system made the crosstalk between liver-on-a-chip and...
Not many systems can mimic the Aerobic-Anaerobic interface of the large intestine. A not-so-old paper from the Wyss institute creates a hypoxic gradient across their intestine-on-a-chip. In this study, the chip comprised epithelial cells on top of a porous membrane and bacteria cultured above the epithelium under a hypoxia...
