This is a common question: what extracellular matrix (ECM) should I use? Specifically, the choice of matrix is very important to mimic the tumor–stromal cells interaction during cancer intravasation. This paper by Agrawal et al. from the Moeendarbary lab at University College London uses a tumor on a chip...
Adding perfusion to organ on a chip devices adds a layer of complexity, so we need to see clear added values to introduce flow in an in vitro system.Here are a few examples of why perfusion could be useful in organ on a chip.Any comments or questions? Please feel...
Shear stress on cells in an organ on a chip is due to the movement of culture medium on top of the cells. It is a force per unit area parallel to the cell layer. Flow in a rectangular microchannel increases with flow rate but increases even faster with...
It is easy to confuse diffusion with flow. In simple terms: Diffusion: due to a concentration gradient of a solute, molecules move in the medium from a higher to lower concentration. Flow: Due to a pressure gradient in the medium, the medium itself moves from a higher to a...
10 key features Multi-organ-on-chips should have for drug disposition assessment as alternative to animal testing.These are the highlights of our recent paper written by Dr. Damiën van Berlo, Dr. Evita van de Steeg and Prof. Roos Masereeuw.Also check out the systematic biological and technical categorization of available multi-organ-on-chip models....
Many organ on a chip systems use pumps to perfuse the micro-tissues they model, or in engineering terms, they have “flow” in the system. But you pay a price here: adding perfusion makes the system more complex! So, you really need to think: Do I really need perfusion in...
Intestine & Intestine-microbiome on chip MasterClass 2025
€1,175.00 – €1,800.00 (excl. VAT)
Organ on a chip MasterClass Turkey 2024
Organ on a chip Digital Platform
€295.00 – €895.00 (excl. VAT)
Organ on a chip MasterClass London 2024
Organ on a chip MasterClass - Intestine & Intestine-microbiome 2024