Intestinal organoids have found application in modeling intestinal function and infection, but is it feasible to replicate gastrointestinal motility and microbiome stability with organoids? One of the limitations is to access their lumens and modify their contents. A challenge that Ginga et al. at the Georgia Institute of Technology...
A recent paper by Kim and Chung groups from the Catholic University of Korea culturing vascularized organoids in a kidney on a chip platform and studying the role of shear stress on the formation and nephrotoxicity of the organoids. The authors cultured organoids in a static culture and injected...
A beautiful paper from Hasse lab at EMBL Barcelona modelling fibrosis in the lung and heart to study the implications of fibrosis on microvasculature. They used a macro-scale side-by-side channel chip, previously developed in the lab of Roger Kamm. The authors developed this vasculature on a chip to assess...
