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Tag: Liver on a chip

HomeBlogLiver on a chip
  • 19

    Liver-on-a-chip and mathematical modeling for drug metabolism studies

    Can organ on a chip systems be adopted for ADME and quantitative drug metabolism studies? This is a recent paper from Docci et al. from the University of Basel that use the liver on a chip from Cn-bio to estimate pharmacokinetic parameters and drug metabolism of cultured primary hepatocytes...

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  • 09

    Multi-organ model of thyroid-liver axis to study endocrine disruption

    A beautiful thyroid-liver axis model of endocrine disruption studying the thyroid-stimulating hormone (TSH)-dependent triiodothyronine (T3) secretion in a dynamic multi-organ chip. This is a joint publication between Bayer and TissUse with a beautiful characterization of the 3D liver and thyroid models. ResultsThe authors used different concentrations of TSH to...

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  • 21

    Liver pancreas crosstalk in organ on a chip to study type 2 Diabetes

    A beautiful paper from Jianhua Qin’s lab from the Chinese Academy of Sciences modelling Liver–pancreatic Islet Axis. They used a multi-organoid organ on a chip system to study glucose regulation in physiological and pathological conditions. After culturing the hiPSCs in “micro-wells” and creating embryonic bodies, the authors differentiated them...

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  • 03

    High throughput Organ on a chip plate

    A new paper from DRAPER, not a lot of manuscripts get accepted only after 2 months like this one! This organ on a chip platform may be less known, but definitely has features that catch eyes: Positive points+ A higher throughput platform with 96 chips in one plate+ Double...

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